April 25-29, 2006 the International Center for Spiritual Renewal facilitated and hosted the Azusa Street Centennial. This 100 year anniversary celebration of the Azusa Street Revival was attended by over 50,000 people from 106 different nations. The streams of Spirit-filled Christianity converged in Los Angeles to rejoice in a century of blessing on this movement that now numbers over 600 million people around the world.

In 2008, the new Oral Roberts University Board of Trustees began work on clarifying the mission of the university for 21st century ministry. An initiative was launched by the Board of Trustees called Empowered21 and the International Center for Spiritual Renewal was asked to facilitate this process to focus on new generations and the power of the Holy Spirit. Immediately, it was discerned that the convergence of these dynamics was leading toward questions and answers that would serve the entire Spirit-filled movement. Empowered21 began to be understood as a natural kingdom-wide follow-up to the Azusa Street Centennial. The Azusa Centennial reflected on what God had done for the last 100 years, and Empowered21 would focus on the future of the movement.